What is the KISSPEPTIN-10?

KISSPEPTIN-10 is , while it's Molecular Formula is C63H83 N17 O14. Metastin (45-54) is a potent and selective agonist of AXOR12 and hOT7T175.

What is the CAS number for KISSPEPTIN-10?

The CAS number of KISSPEPTIN-10 is 374675-21-5.

What is KISSPEPTIN-10 (374675-21-5) used for?

Metastin (45-54) is a 10 amino acid peptide that corresponds to the bioactive C-terminal 45-54 amino acids of metastin, a metastasis suppressor gene product. It acts as a potent agonist of GPR54 (OT7T175, AXOR12), with approximately 8-fold higher binding affinity than metastin (Ki values of 0.042 and 0.34 nM, respectively, for displacement of metastin (40-54)). Metastin (45-54) induces calcium mobilization in GPR54-transfected cells (EC50 = 0.18-1.1 nM). It inhibits the migration of GPR54-transfected CHO cells at concentrations of 10-100 nM, equaling the potency of full length metastin.