Question 1

What is the Liraglutide?

Accepted Answer

Liraglutide is , while it's Molecular Formula is C172H265N43O51.  Liraglutide is a new type of hypoglycemic drug that activates AMP-activated protein kinase thus enhancing insulin sensitivity. It not only has a significant hypoglycemic effect, but also has the functions of weight loss, blood pressure reduction, and improvement of blood lipid profile.Liraglutide, a human glucagon-like peptide-1 (GLP-1) receptor agonist, slows gastric emptying, increases satiety, and reduces patient eating, while reducing the brain's desire to eat and allowing the body to Increased energy expenditure plays a role in weight loss; it prevents the liver from producing too much glucose and promotes the pancreas to produce more insulin to lower blood sugar; in addition, liraglutide also has cardiovascular benefits and kidney protection.

Question 2

What is the CAS number for Liraglutide?

Accepted Answer

The CAS number of Liraglutide is 204656-20-2.

Question 3

What is Liraglutide (204656-20-2) used for?

Accepted Answer

Liraglutide, also known as Victoza, is a human glucagon-like peptide-1 (GLP-1) receptor agonist used as a treatment for type 2 diabetes mellitus (T2DM). It is a long-acting GLP-1 analog designed to bind to albumin, which serves as the main molecular mechanism of protraction. Liraglutide is a modified GLP-1(1–37) with lysine at position 34 replaced by arginine and a hexadecanoyl group attached to the remaining lysine via a glutamic acid spacer. This modification allows for a greatly extended serum half-life of approximately 10 to 15 hours after subcutaneous administration, enabling once-daily dosing. Liraglutide is characterized as a white to almost white powder and is soluble in aqueous base solutions, methanol, and very slightly soluble in ethanol.InChI:InChI=1/C172H265N43O51/c1-18-20-21-22-23-24-25-26-27-28-29-30-37-53-128(223)193-112(59-64-132(227)228)148(244)180-68-41-40-50-111(154(250)199-116(62-67-135(233)234)155(251)204-120(73-100-44-33-31-34-45-100)160(256)214-140(93(11)19-2)168(264)192-97(15)146(242)201-122(76-103-79-183-108-49-39-38-48-106(103)108)158(254)203-118(72-90(5)6)159(255)212-138(91(7)8)166(262)200-110(52-43-70-182-172(177)178)150(246)184-81-129(224)194-109(51-42-69-181-171(175)176)149(245)187-84-137(237)238)196-144(240)95(13)189-143(239)94(12)191-153(249)115(58-63-127(174)222)195-130(225)82-185-152(248)114(61-66-134(231)232)198-156(252)117(71-89(3)4)202-157(253)119(75-102-54-56-105(221)57-55-102)205-163(259)124(85-216)208-165(261)126(87-218)209-167(263)139(92(9)10)213-162(258)123(78-136(235)236)206-164(260)125(86-217)210-170(266)142(99(17)220)215-161(257)121(74-101-46-35-32-36-47-101)207-169(265)141(98(16)219)211-131(226)83-186-151(247)113(60-65-133(229)230)197-145(241)96(14)190-147(243)107(173)77-104-80-179-88-188-104/h31-36,38-39,44-49,5

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